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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Br J Haematol. 2014 Aug 12;167(4):453–465. doi: 10.1111/bjh.13064

Table II. Desmopressin doses and response for VWD.

Route of administration Suggested formulation Dose Peak levels achieved
Intravenous infusion over 30-60 min 4 μg/ml diluted in 100ml 0.9%NaCl for infusion 0.3 μg/kg [maximum dose 28 μg] 15 min after infusion completed
Subcutaneous 15 μg/ml 0.3 μg/kg [maximum dose 28 μg] 60-90 min after injection
Intranasal 150 μg per metered spray > 50 kg: 150 μg spray to each nostril
≤ 50 kg: single 150 μg spray
1-4 h after administration