Table 3.
Table of ROIs that exhibit FDR-significant (Benjamini and Hochberg, 1995) differences between CTL and either AD or l-MCI subjects, and associations with MMSE cognitive scores. Here we show the total length of each tract’s mean MDP, as well the number of points that are FDR-significant followed by the percentage of mean MDP tract points that show significant group differences.
| ROI | Length | AD vs CTL | CTL vs l-MCI | MMSE | |||
|---|---|---|---|---|---|---|---|
| FA | MD | FA | MD | FA | MD | ||
| p<0.010 | p<0.030 | -- | p<0.001 | p<0.003 | p<0.029 | ||
| CGC L | 59 | 23 (39.0 %) | 22 (37.3%) | -- | -- | 2 (3.4%) | 16 (27.1%) |
| CGC R | 64 | 11 (17.2 %) | 11 (17.2%) | -- | -- | 5 (7.8%) | 10 (15.6%) |
| CGH L | 25 | -- | 22 (88.0%) | -- | -- | -- | 21 (84.0%) |
| CGH R | 18 | 5 (27.8%) | 18 (100%) | -- | 2 (11.1%) | -- | 18 (100%) |
| IFO L | 67 | 12 (17.9 %) | 45 (67.2%) | -- | -- | 5 (7.5%) | 51 (76.1%) |
| IFO R | 60 | 2 (3.3%) | 45 (75.0%) | -- | -- | 10 (16.7%) | 44 (73.3%) |
| ILF L | 42 | 5 (11.9%) | 35 (83.3%) | -- | 3 (7.1%) | -- | 42 (100%) |
| ILF R | 42 | -- | 42 (100%) | -- | -- | -- | 38 (90.5%) |
| SLF L | 35 | -- | 18 (51.4%) | -- | -- | -- | 20 (57.1%) |
| SLF R | 33 | -- | 24 (72.7%) | -- | -- | -- | 29 (87.9%) |
| UNC L | 23 | 6 (26.1%) | 23 (100%) | -- | 2 (8.7%) | 3 (13.0%) | 22 (95.7%) |
| UNC R | 19 | -- | 15 (78.9%) | -- | -- | -- | 18 (94.7%) |
| CC_Cing | 71 | 10 (14.1%) | 21 (29.6%) | -- | -- | -- | 23 (32.4%) |
| CC_Cu | 31 | 5 (16.1%) | 13 (41.9%) | -- | -- | -- | 5 (16.1%) |
| CC_LG | 37 | 2 (5.4%) | 24 (64.9%) | -- | 3 (8.1%) | -- | 15 (40.5%) |
| CC_MFG | 25 | 5 (20.0 %) | 17 (68.0%) | -- | -- | 3 (12.0%) | 18 (72.0%) |
| CC_MOG | 58 | 11 (19.0%) | 20 (34.5%) | -- | -- | 2 (3.4%) | 29 (50.0%) |
| CC_PoCG | 42 | 21 (50.0%) | 30 (71.4%) | -- | -- | -- | 18 (42.9%) |
| CC_PrCG | 42 | 8 (19.0%) | 22 (52.4%) | -- | -- | -- | 15 (35.7%) |
| CC_PrCu | 41 | 25 (61.0%) | 30 (73.2%) | -- | 2 (4.9%) | 16 (39.0%) | 34 (82.9%) |
| CC_RG | 29 | 1 (3.4%) | 27 (93.1%) | -- | -- | -- | 29 (100%) |
| CC_SFG | 120 | 25 (20.8%) | 57 (47.5%) | -- | -- | 4 (3.3%) | 57 (47.5%) |
| CC_SOG | 58 | 14 (24.1%) | 32 (55.2%) | -- | -- | -- | 26 (44.8%) |
| CC_SPG | 39 | 23 (59.0%) | 28 (71.8%) | -- | -- | 15 (38.5%) | 27 (69.2%) |