Table 1.
LVAD bridge to recovery studies (adapted from [12]).
| Study | Design | N | Standardized Med Therapy |
Duration (mos) |
Recovery* n (%) |
Durability** |
|---|---|---|---|---|---|---|
| LVAD Working Group, 2007 [45] | P | 67 | N | 4.5 | 6 (9) | 100/6m |
| Berlin, 2008 and 2011 [46, 47] | P | 188 | N | 4 | 35 (19) | 74/3y; 66/5y |
| Harefield, 2006 [6] | P | 15 | Y | 11 | 11 (73) | 100/1y; 89/4y |
| Harefield, 2011 [5] | P | 20 | Y | 9 | 12 (60) | 88/3y |
| Athens-Harefield, 2007 [48] | P | 8 | Y | 7 | 4 (50) | 100/2y |
| Vancouver, 2011 [49] | P | 17 | N | 7 | 4 (23) | 100/2y |
| Gothenburg, 2007 [50] | P | 18 | N | 7 | 3 (17) | 33/8y |
| Pittsburgh, 2003 [51] | R | 18 | N | 8 | 6 (33) | 67/1y |
| Osaka, 2005 [52] | R | 11 | N | 15 | 5 (45) | 100/8–29m |
| Pittsburgh, 2010 [53] | R | 102 | N/A | 5 | 14 (14) | 71/5y |
| Multicenter, 2002 [54] | R | 271 | N/A | 2 | 22 (8) | 77/3y |
| Columbia, 1998 [55] | R | 111 | N/A | 6 | 5 (4.5) | 20/15m |
| Montefiore, 2013 [20] | P | 21 | Y | ? | 5 (23%) | 100/>3y |
P, prospective; R, retrospective; NA, not applicable; HF, heart failure.
*
Recovery defined as LVAD explantation as a result of functional myocardial recovery.
**
Durability defined as freedom from LVAD reimplantation or transplant - percentage over mean years of follow-up.