Table 1.
Descriptive statistics of patient demographics basic hemodynamic data, global cardiac function parameters and global myocardial velocities
| all patients | sub-group by LVEF | p-value | ||
|---|---|---|---|---|
| low (<50%) | preserved (>50%) | |||
| N | 31 | 12 | 19 | |
| age [years] | 50±18 (54, 32) | 45±18 (31, 21) | 53±18 (59, 30) | 0.20* |
| LVEF [%] | 49±17 (54, 21) | 31±12* (31, 22) | 60±5 (61, 9) | <0.001* |
| EDV [ml] | 170±68 (165, 69) | 219±69* (199, 74) | 138±47 (133, 52) | 0.001* |
| ESV [ml] | 95±68 (68, 63) | 156±73* (139, 97) | 56±20 (53, 25) | <0.001* |
| native T1 [ms] | 1002±52 (995, 66) | 1004±44 (994, 39) | 1001±57 (995, 70) | 0.86* |
| SV [ml] | 74±28 (72, 35) | 60±21* (57, 16) | 82±29 (80, 31) | 0.032* |
| LV mass [g] | 128±50 (123, 63) | 153±57* (145, 79) | 113±40 (116, 58) | 0.030* |
| LV mass-to-volume ratio | 0.79±0.22 (0.79, 0.35) | 0.71±0.21 (0.71, 0.25) | 0.84±0.21 (0.89, 0.29) | 0.10* |
| heart rate [bpm] | 84±17 (82, 25) | 89±21 (85, 31) | 82±14 (80, 20) | 0.28* |
| systolic blood pressure [mmHg] | 123±21 (120, 24) | 125±22 (125, 41) | 122±21 (116, 21) | 0.66* |
| diastolic blood pressure [mmHg] | 78±14 (74, 20) | 79±16 (77, 25) | 77±12 (72, 18) | 0.59* |
| Number of LV segments with LGE | 2.3±3.3 (1.0, 3.0) | 1.3±1.6 (1.0, 2.3) | 2.9±4.0 (2.0, 3.5) | 0.31# |
| ECV [%] | 0.29±0.08 (0.28, 0.02) | 0.28±0.06 (0.27, 0.06) | 0.30±0.09 (0.29, 0.06) | 0.36# |
| radial vel. systole [cm/s] | 2.9±1.0 (2.6, 0.6) | 2.4±0.8* (2.5, 0.9) | 3.2±1.0 (2.9, 0.4) | 0.006# |
| radial vel. diastole [cm/s] | −3.9±1.0 (−3.6, 1.4) | −3.9±0.8 (−3.6, 1.3) | −4.0±1.1 (−3.6, 1.4) | 0.80* |
| long-ax vel. systole [cm/s] | 4.6±1.8 (4.6, 2.9) | 4.2±2.0 (3.6, 3.7) | 4.8±1.6 (5.1, 2.6) | 0.41* |
| long-ax vel. diastole [cm/s] | −4.9±1.7 (−4.8, 1.9) | −4.9±1.1 (−4.8, 1.7) | −4.9±2.0 (−4.4, 2.5) | 0.99* |
p-values: differences between sub-groups with low versus preserved LVEF for Gaussian distributions
*
t-tests and non-normal distributions
#
Mann-Whitney tests
Patient demographics, basic hemodynamic data, global cardiac function parameters and global myocardial velocities (averaged over all 16 segments of the LV) for the entire study cohort and for subgroups with low and preserved LVEF. Differences between sub-groups were evaluated using t-tests for Gaussian distributions (*). Otherwise, Mann-Whitney tests (#) were used. All data are presented as mean ± standard deviation (median, interquartile range).