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. 2015 Jan 5;8:406. doi: 10.3389/fnbeh.2014.00406

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Copyright © 2015 Galeano, Blanco, Logica Tornatore, Romero, Holubiec, Rodríguez de Fonseca and Capani.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Middle-aged rats reared in an enriched environment showed reduced anxiety-related behaviors in the Elevated Plus Maze test. (A) Total distance traveled; (B) number of closed arm entries; (C) percentage of open arms entries; (D) percentage of time spent in open arms. CTL, vaginal delivery rats; C+, rats born by cesarean section; PA, rats born by cesarean section + asphyxia; SE, standard environment; EE, enriched environment. Each bar represents the mean + s.e.m. of n = 12. ^**p < 0.01; ^***p < 0.001.