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. 2014 Dec 29;9(12):e116306. doi: 10.1371/journal.pone.0116306

Figure 2. Changes in peripheral blood T cell activation and soluble markers of inflammation during mesalamine.

Figure 2

Estimated mean changes (with 95% CI) in the frequency of activated (CD38+ HLA-DR+) CD8+ (A) and CD4+ (B) T cells, sCD14 (C), IL-6 (D), D-dimer (E), and kynurenine to tryptophan (K:T) ratio (F) in peripheral blood are plotted for placebo-treated (blue) and mesalamine-treated (red) subjects. P values are provided for the changes within each indicated interval both within arms and between arms.