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Proposed model for the regulation of meiotic progression by RNA-binding proteins. In this model, DAZL is a translational regulator of VASA and SCP3. Thus, VASA is implicated in NANOS3 regulation as well in mei-P26 and PIWI proteins that control piRNA expression. These piRNAs silence retro-transposons, which is necessary for the correct MSUC and meiotic progression.
