Table 3.
Confirmation of results by family history prediction method
Change | BRCAPro Score | # ovarian tumors | Dx Age | Predicted probability of being deleterious | Classificationa |
---|---|---|---|---|---|
L22S | 0.497 | 1 | 38 | 0.9993 | Deleterious |
T37K | 0.997 | 3 | 27 | 1.0000 | Deleterious |
K45Q | 0.05 | 0 | 60 | 0.1135 | Neutral |
Classification using the Gomez Garcia model as described [16];
, Number; Dx Age, Age proband was first diagnosed with cancer