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. 2014 Dec 30;10:245–256. doi: 10.2147/IJN.S74868

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© 2015 Zhao et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Intracellular adenosine triphosphate level assay after 48 hours’ incubation with free 5-Fu, 5-Fu-loaded mAb GRP78-NPs, and 5-Fu-loaded IgG-NPs.

Notes: (A) SMMC-7721 cells. *P<0.05, ***P<0.001 versus the free 5-Fu group. (B) PLC cells. *P<0.05, **P<0.01 versus the free 5-Fu group. Results are expressed as means ± SD (n=3).

Abbreviations: 5-Fu, 5-fluorouracil; CR, changing rates of intracellular ATP level; IgG-NPs, NPs conjugated with IgG; mAb GRP78-NPs, NPs conjugated with monoclonal antibody against GRP78; NPs, nanoparticles; SD, standard deviation.