Table 3.
Adverse events of withdrawal patients according to treatment groups (genotype 1)
| Adverse events | PEG-IFN alfa-2a n=2,874 | PEG-IFN alfa-2b n=5,564 | P-value |
|---|---|---|---|
|
| |||
| N (%) | |||
| Fatigue | 144 (5.0) | 294 (5.3) | 0.605 |
| Interstitial pneumonia | 21 (0.7) | 32 (0.6) | 0.387 |
| Stroke | 2 (0.1) | 6 (0.1) | 0.724 |
| Anemia | 50 (1.7) | 119 (2.1) | 0.251 |
| Decreased appetite | 90 (3.1) | 179 (3.2) | 0.896 |
| Thrombocytopenia | 46 (1.6) | 50 (0.9) | 0.005 |
| Psychiatric disorders | 63 (2.2) | 137 (2.5) | 0.497 |
| Retinopathy | 13 (0.5) | 44 (0.8) | 0.091 |
| Other | 145 (5.0) | 274 (4.9) | 0.833 |
Abbreviation: PEG-IFN, pegylated interferon.