Table 2.
Reverse single-step transepithelial PRK for high myopia: visual and refractive outcomes compared to PRK and LASIK control groups
| tPRK | PRK | LASIK | P-value (tPRK vs PRK) | P-value (tPRK vs LASIK) | |
|---|---|---|---|---|---|
| Efficacy and safety at 12 months | |||||
| Number of eyes | 35 | 28 | 31 | ||
| Postoperative logMAR UDVA (SD) | 0.00 (0.05) | 0.06 (0.1) | 0.05 (0.09) | 0.01 | 0.008 |
| 20/25 equivalent or better UDVA (%) | 97.1 | 75.0 | 87.1 | 0.51 | 0.02 |
| 20/20 equivalent or better UDVA (%) | 77.1 | 60.7 | 48.3 | 0.30 | 0.09 |
| Loss of 2 or more lines CDVA (%) | 0 | 14.3 | 0 | 0.03 | 1 |
| Refractive outcomes 12 months postoperatively | |||||
| Mean postoperative SE, D (SD) | −0.10 (0.34) | −0.20 (0.59) | −0.08 (0.36) | 0.4 | 0.72 |
| % within ±0.5 D target | 91.4 | 85.7 | 83.9 | 0.68 | 0.45 |
| % within ±1.0 D target | 97.1 | 89.3 | 100 | 0.31 | 1 |
Abbreviations: CDVA, corrected distance visual acuity; D, diopters; LASIK, laser-assisted in situ keratomileusis; logMAR, logarithm of the minimum angle of resolution; SD, standard deviation; SE, spherical equivalent; PRK, photorefractive keratectomy; tPRK, transepithelial PRK; UDVA, uncorrected distance visual acuity; vs, versus.