Table 3.

Cause-specific adjusted mortality rate ratios by smoking status.

	All cohorts (79 760 person-years follow-up)		Cohorts with information on current, previous and never-smokers (32 983 person-years follow-up)
	Deaths	MRR (95% CI) Smoker versus nonsmoker	Deaths	MRR (95% CI) Current versus never smoker	MRR (95% CI) Previous versus never smoker
AIDS-related deaths	152	1.37 (0.93–2.02)	99	1.21 (0.73–2.01)	0.54 (0.28–1.03)
Non-AIDS related deaths	276	2.61 (1.88–3.61)	153	2.45 (1.49–4.03)	1.40 (0.81–2.42)
Non-AIDS malignancies	94	3.13 (1.80–5.45)	43	2.42 (1.03–5.68)	0.94 (0.34–2.64)
Cardiovascular disease	39	6.28 (2.19–18.0)	27	8.82 (1.15–67.8)	4.55 (0.55–37.6)
Non-AIDS infections	26	2.38 (0.88–2.46)	10	3.98 (0.47–15.8)	1.38 (0.12–15.8)
Liver disease	19	8.70 (1.14–66.6)	14	3.44 (0.42–28.4)	1.46 (0.15–14.4)
Other	66	1.42 (0.81–2.49)	29	1.08 (0.40–2.93)	0.66 (0.22–1.98)
Non-AIDS, not classified	32	2.56 (0.96–6.83)	30	1.90 (0.61–5.96)	2.34 (0.73–7.43)
Accident/violence/suicide/substance abuse	36	2.30 (0.92–5.77)	24	2.14 (0.60–7.60)	0.38 (0.06–2.36)
Unknown	56	1.38 (0.78–2.46)	25	0.93 (0.30–2.87)	1.27 (0.41–3.92)

MRRs adjusted for sex, age (time-updated), route of transmission, CD4⁺ cell count at baseline, AIDS at ART initiation, years on ART (time-updated) and calendar year of ART. MRR, mortality rate ratio.