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. Author manuscript; available in PMC: 2015 Jan 5.
Published in final edited form as: Transfus Med Rev. 2013 Oct 3;27(4):241–248. doi: 10.1016/j.tmrv.2013.08.002

Figure 2. Indirect and Direct Pathways of Antigen Presentation.

Figure 2

In the indirect pathway (top) donor antigens are processed and presented by recipient antigen presenting cells (APC). In the direct pathway, donor APCs, with their own peptides presented on MHC, stimulate recipient T cells.