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Sgf73 influences silencing at rDNA and telomeres. (A) Sir2 protein levels are unchanged in sgf73Δ; (B) rDNA-dependent recombination of an ADE2 locus is dramatically reduced in sgf73Δ. At telomeres, sgf73Δshows increased silencing of URA3 marker on VIIL (C), but decreased silencing of endogenous ORF YFR057W on VIR (D). Error bars indicate standard error of the mean. See also Supplemental Figure S6.
