Table 2.
Descriptive statistics for physiological dysregulation summary scores and subscores by sex and study
| Biomarker | Observed Rangea | % Scoring Zero | Age adjusted Mean | Standard error |
|---|---|---|---|---|
| SEBAS Males (n=526)b | ||||
| Overall Physiological Dysregulationc | 0-13 | 2.3 | 5.1 | 0.20 |
| CV/metabolic Subscore | 0-7 | 8.9 | 2.5 | 0.11 |
| HPA/SNS Function Subscore | 0-4 | 56.3 | 0.6 | 0.06 |
| Inflammation Subscore | 0-6 | 39.2 | 1.5 | 0.12 |
| SEBAS Females (n=450)b | ||||
| Overall Physiological Dysregulationc | 0-14 | 0.2 | 5.0 | 0.13 |
| CV/metabolic Subscore | 0-7 | 6.2 | 2.4 | 0.08 |
| HPA/SNS Function Subscore | 0-4 | 25.8 | 1.2 | 0.05 |
| Inflammation Subscore | 0-6 | 37.8 | 1.1 | 0.06 |
| MIDUS Males (n=460) | ||||
| Overall Physiological Dysregulationc | 0-13 | 2.8 | 4.7 | 0.17 |
| CV/metabolic Subscore | 0-9 | 7.2 | 3.1 | 0.13 |
| HPA/SNS Function Subscore | 0-3 | 53.7 | 0.5 | 0.03 |
| Inflammation Subscore | 0-6 | 42.6 | 1.0 | 0.07 |
| MIDUS Females (n=554) | ||||
| Overall Physiological Dysregulationc | 0-13 | 3.4 | 4.1 | 0.14 |
| CVD/metabolic Subscore | 0-8 | 13.4 | 2.1 | 0.09 |
| HPA/SNS Function Subscore | 0-4 | 35.0 | 0.7 | 0.04 |
| Inflammation Subscore | 0-6 | 34.7 | 1.2 | 0.07 |
a
The theoretical ranges of the summary scores are as follows: PD - 0 to 20; CV/metabolic – 0 to 9; HPA/SNS – 0 to 4; Inflammation – 0 to 6;
b
The SEBAS distributions are weighted to account for oversampling of older respondents and urban residents
c
One biomarker (creatinine clearance) is not included in any of the subscores.