Table 3.
Outcomes (Type of Model)
|
||||||||
---|---|---|---|---|---|---|---|---|
SEBAS Males | MIDUS Males | |||||||
|
|
|||||||
PD (NB) | CV/metabolic (P) | HPA/SNS (P) | INF (ZINB) | PD (NB) | CV/metabolic (NB) | HPA/SNS (P) | INF (ZINB)d | |
Education Model (includes age, age-squared, race/ethnicity, education a) | ||||||||
(Low education omitted) | ||||||||
Medium education | 0.95 | 0.95 | 1.10 | 0.90 | 0.94 | 0.94 | 0.91 | 0.97 |
High education | 0.82** | 0.92 | 0.73 | 0.68** | 0.71** | 0.76** | 0.67* | 0.62** |
p-value medium vs. high education | 0.007 | 0.586 | 0.002 | 0.007 | <0.001 | 0.001 | 0.042 | <0.001 |
χ2 (2 df) | 10.77** | 1.02 | 9.69** | 11.39** | 34.92** | 19.03** | 7.84* | 19.21** |
Income Models (includes age, age-squared, race/ethnicity, income quartiles b) | ||||||||
(Q1 omitted) | ||||||||
Q2 | 1.00 | 0.95 | 0.90 | 1.07 | 0.83* | 0.88 | 0.89 | 0.70* |
Q3 | 0.91 | 0.94 | 0.92 | 0.83 | 0.96 | 0.97 | 1.09 | 0.91 |
Q4 | 0.78** | 0.88 | 0.58** | 0.67** | 0.77** | 0.82* | 0.80 | 0.65** |
p-value Q2 vs. Q3 | 0.176 | 0.893 | 0.885 | 0.038 | 0.052 | 0.238 | 0.247 | 0.085 |
p-value Q3 vs. Q4 | 0.023 | 0.416 | 0.008 | 0.120 | 0.004 | 0.029 | 0.083 | 0.022 |
χ2 (3 df) | 14.66** | 1.91 | 9.64* | 13.41** | 14.40** | 7.33 | 3.39 | 10.71* |
Ladder Score Models (includes age, age-squared, race/ethnicity, ladder score c) | ||||||||
(Low ladder score omitted) | ||||||||
Middle ladder score | 0.92 | 0.97 | 0.81 | 0.85 | 0.91 | 1.00 | 0.87 | 0.72* |
High ladder score | 0.84** | 0.93 | 0.78 | 0.73** | 0.90 | 0.96 | 0.93 | 0.73* |
p-value for middle vs. high | 0.250 | 0.533 | 0.831 | 0.269 | 0.800 | 0.546 | 0.667 | 0.921 |
χ2 (2 df) | 8.18* | 1.14 | 4.16 | 8.31* | 3.42 | 0.51 | 0.74 | 8.46* |
| ||||||||
n | 526 | 460 |
Note. SEBAS = Social Environment and Biomarkers of Aging Study; MIDUS = Midlife in the United States; PD = physiological dysregulation; NB = negative binomial regression model; CV/metabolic = cardiovascular and metabolic function score; P = Poisson regression model; HPA/SNS = hypothalamic–pituitary–adrenal axis and sympathetic nervous system; INF = inflammation score; ZINB = zero-inflated negative binomial.
SEBAS education categories: for males, low= 0-5 years, medium=6 years, and high= 7+ years; for females, low= 0 years, medium=1-6 years, and high=7+ years. MIDUS education categories are: high school or less, some college/2 yr degree, and 4-5 yr college degree or more.
Income quartiles SEBAS: Q1=NT$0 - NT$144,000; Q2=NT$145,500-NT$270,000; Q3=NT$271,500-NT$605,000; and Q4=NT$620,000-NT$860,000. Income quartiles MIDUS: Q1=$0-$39,000; Q2=$39,024 - $62,500; Q3 = $62,750-$101,250; and Q4 = $101,500-$400,000. Note that 1 NT$ = 0.33 US$.
SEBAS ladder score categories: low=rungs 0-4; medium=rung 5; high=rungs 6-10. MIDUS ladder score categories: low=rungs 0-6; medium=rung 7; high=rungs 8-10.
The best fitting model for regressing the inflammation score on ladder score is the negative binomial regression model.
p < 0.05;
p<0.01