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Immunoelectron microscopy identifies a 27-nm particle associated with acute infectious nonbacterial gastroenteritis. Shown is an aggregate observed after incubation of a second-passage stool filtrate from the original Norwalk outbreak with a 1:10 dilution of postchallenge antiserum of an experimentally infected volunteer. These particles are heavily coated with antibody. (Adapted from reference 1 with permission.)
