TABLE 7.
Performance of norovirus rapid antigen immunochromatographic assays
| Study reference | Test | Study location | Case context | Population(s) | Sensitivity (%) | Specificity (%) | Reference method (reference[s]) |
|---|---|---|---|---|---|---|---|
| 382 | Laboratory developed | Japan | Sporadic | Pediatric | 69.8 | 93.7 | Conventional RT-PCR (383) |
| 384 | Ridaquicka | Australia | Not specified | Not specified | 82.0 | 100.0 | Real-time RT-PCR (198) |
| 385 | Ridaquick | Netherlands | Not specified | Not specified | 57.1 | 99.1 | Real-time RT-PCR (195) |
| 375 | Ridaquick | Brazil | Sporadic | Pediatric | 69.0 | 98.0 | Real-time/conventional RT-PCR (284, 298) |
| 386 | Ridaquick | Australia | Sporadic, outbreak | Not specified | 83.0 | 100.0 | Compositeb |
| 387 | Ridaquick | USA | Not specified | Not specified | 61.4 | 100.0 | Real-time RT-PCR (387) |
| 379 | Ridaquick | Germany | Sporadic | Not specified | 69.0 | 97.0 | Compositec |
| 388 | SD Biolined | South Korea | Not specified | Pediatric, adult | 90.2 | 100.0 | Real-time RT-PCRe |
| 389 | SD Bioline | South Korea | Sporadic | Pediatric, adult | 76.5 | 99.7 | Real-time RT-PCRf |
| 390 | Ridaquick | Thailand | Sporadic | Not specified | 48.2 | 87.5 | Nested/real-time RT-PCRg |
| 391 | Ridaquick | France | Not specified | Not specified | 17.0 | 100.0 | Conventional RT-PCR (392) |
| ImmunoCardSTAT!h | 26.0 | 100.0 | |||||
| Norotopi | 52.0 | 100.0 | |||||
| SD Bioline | 23.0 | 100.0 |
R-Biopharm, Darmstadt, Germany.
Utilizes a diagnostic algorithm that takes into account electron microscopy and six conventional RT-PCR assays (386).
At least 2 positive real-time RT-PCR test results by SmartNorovirus (Cepheid, Sunnyvale, CA), Ridagene Norovirus LC (R-Biopharm, Darmstadt, Germany), and an assay developed at the Robert Koch Institute (195) are considered a true-positive result.
Standard Diagnostics, Inc., Kyonggi-do, South Korea.
Ridagene Norovirus (R-Biopharm, Darmstadt, Germany) and AccuPower Norovirus real-time RT-PCR kit (Bioneer, Daejeon, South Korea).
AccuPower Norovirus real-time RT-PCR kit (Bioneer, Daejeon, South Korea).
Norovirus real-time RT-PCR kit (Shanghai ZJ Bio-Tech, Shanghai, China) and nested RT-PCR (393).
Meridian Bioscience Europe, Nice, France.
All.Diag SA, Strasbourg, France.