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(a) Eμ-TCL1FL construct. (b) Tcl1 expression in Eμ-TCL1FL transgenic mouse model. Western blot analysis was carried out using anti-Tcl1 antibodies. wild-type spleen lysate from wild-type control. FL1 and FL4 spleen lysates from FL1 and FL4 transgenic lines. (c) Gross pathology of a representative 18 months old Eμ-TCL1FL transgenic mouse (right), and a wild-type control of the same age (left).
