. 2015 Jan 7;21(1):124–131. doi: 10.3748/wjg.v21.i1.124

Table 1.

Randomized controlled trials included in the analysis[10-12,18]

RCT	Year	Treatment	Endpoint	Size	Number of cysts per group	Mean cyst size (cm)	P < 0.05	Jadad Score
Khuroo et al[34]	1993	ALB flow diagram s PD vs ALB+ PD	Echo P	33	10, 12, 11	9.2 ± 4.4; 10.8 ± 3; 8.8 ± 4.5	Yes	2
Khuroo et al[34]	1993	ALB flow diagram s PD vs ALB+ PD	Echo P	33	10, 12, 11	9.2 ± 4.4; 10.8 ± 3; 8.8 ± 4.5	ALB + PD > ALB alone	2
Gil-Grande et al[7]	1993	ALB 1-3 mo vs PLB + S	Viability	55	18, 18, 19	10.4 ± 4; 8.9¹ ± 4; 10.5 ± 5	Yes	5
Gil-Grande et al[7]	1993	ALB 1-3 mo vs PLB + S	Viability	55	18, 18, 19	10.4 ± 4; 8.9¹ ± 4; 10.5 ± 5	ALB 3 mo > ALB 1 mo > no ALB	5
Khuroo et al[35]	1997	ALB + PD vs S alone	Echo P	50	25, 25	8 ± 3; 9.1 ± 3	Yes	3
Khuroo et al[35]	1997	ALB + PD vs S alone	Echo P	50	25, 25	8 ± 3; 9.1 ± 3	ALB + PD > S alone	3
Dziri et al[54]	1999	OP vs no OP	Deep abscess	115	58, 57	50; 50²	Yes	2
Dziri et al[54]	1999	OP vs no OP	Deep abscess	115	58, 57	50; 50²	OP > no OP	2
Franchi et al[6]	1999	ALB vs MBZ	Echo P	448	178, 440	-	Yes	2
Franchi et al[6]	1999	ALB vs MBZ	Echo P	448	178, 440	-	ALB > MBZ	2
Keshmiri et al[8]	2001	ALB vs PLB	Echo P	29	49, 191	74.01 ± 130.79; 198.13 ± 403.71¹	Yes	4
Keshmiri et al[8]	2001	ALB vs PLB	Echo P	29	49, 191	74.01 ± 130.79; 198.13 ± 403.71¹	ALB > PLB	4
Bildik et al[9]	2007	ALB 1-3 mo vs no ALB + S	Viability	84	-	-	Yes	1
Bildik et al[9]	2007	ALB 1-3 mo vs no ALB + S	Viability	84	-	-	ALB 3 mo > no ALB	1
Yüksel et al[15]	2008	Radical S vs conservative	Early recurrence; cavity complications	32	15, 17	7.8; 8.1	Yes	3
Yüksel et al[15]	2008	Radical S vs conservative	Early recurrence; cavity complications	32	15, 17	7.8; 8.1	Radical > Conservative	3
Shams-Ul-Bari et al[29]	2011	ALB + S vs S alone	Viability	72	36, 36	-	Yes	3
Shams-Ul-Bari et al[29]	2011	ALB + S vs S alone	Viability	72	36, 36	-	ALB + S > S alone	3

Mean volume of cysts in cm³;

Median size of the cavity in cm². Degenerative imaging changes assessed through echography. Viability: Viability of hydatid disease; Echo P: Echo pattern; S: Surgery; ALB: Albendazole; PD: Percutaneous drainage; PLB: Placebo.