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. 2015 Jan 7;21(1):269–275. doi: 10.3748/wjg.v21.i1.269

Table 4.

Small cell neuroendocrine carcinoma of the gallbladder of the literature

Ref. Age (yr) Sex Size (cm) Meta or local inv Mixed tumor Survival (mo) Tumor stage Chromogranin A Recurrence (site) Operation type
Moskal et al[22], 1999 69 F NA Regional LN meta, pancreas inv + 44 T3 NA + (abdomen) Radical
57 F NA Regional LN meta, liver inv - 31 T3 NA + (abdomen, bone) Radical
69 M NA Regional LN meta - 21 T2 NA + (retroperitoneum) C
71 F NA Regional LN meta peritoneum meta + 13 T2 NA + (retroperitoneum) C
40 M NA Regional LN meta + 189, alive T2 NA + (lung, abdomen) C
Maitra et al[21], 2001 85 F 4.0 Liver meta + 13 ≥ T2 + NA Surg
77 F 2.8 Pancreas inv, LN meta + 25 ≥ T2 NA NA Surg
43 F 2.0 Liver meta + 9 ≥ T2 + NA Surg
73 F 2.5 LN meta + 7 ≥ T2 + NA Surg
82 M 1.0 Liver meta + 8 ≥ T2 NA NA Surg
77 F 3.0 - + 10 ≥ T2 + NA Surg
73 M 6.3 Liver meta - 6 ≥ T2 NA NA Surg
71 M NA - - 3 T1 NA NA Surg
37 F 8.0 LN meta - 7 ≥ T2 NA NA Surg
68 M 2.0 LN meta - 14 ≥ T2 + NA Surg
67 F 2.8 - - NA ≥ T2 + NA Surg
78 M 1.8 LN meta - 16 ≥ T2 NA NA Surg
Lane et al[11], 2002 67 M NA - - 11 T1b + + (liver, LN) C
Iype et al[16], 2008 32 F 2.0 Regional LN meta, liver meta - 14, alive T2 + + (liver, LN) Radical
Current study, 2014 49 F 1.9 - - 37, alive T2 + - Radical
66 M 1.5 Regional LN meta + 13, alive T2 + - Radical
63 F 3.0 - - 67, died T2 - + (liver) C
45 F 9.5 LN inv, colon inv, liver inv + 50, alive T3 - - Radical

C: Cholecystectomy; F: Female; inv: Invasion; LN: Lymph node; M: Male; meta: Metastasis; NA: Not available; Surg: Extent of surgery not reported.