Table 4.
Prevalence of the autoantibodies in non-cirrhosis, compensated cirrhosis, and decompensated cirrhosis chronic hepatitis B groups n (%)
Non-cirrhosis (n = 119) |
Compensate cirrhosis (n = 85) |
Decompensated cirrhosis (n = 121) |
||||
Pos. | P value | Pos. | P value | Pos. | P value | |
ANA | 39 (32.8) | 0.006 | 16 (18.8) | 0.027 | 21 (17.4) | 0.787 |
SMA | 1 (0.8) | 0.393 | 3 (3.5) | 0.131 | 6 (5.0) | 0.882 |
AMA-M2 | 9 (7.6) | 0.410 | 4 (4.7) | 0.971 | 9 (7.4) | 0.427 |
Anti-BPO | 4 (3.4) | 0.010 | 11 (12.9) | 0.248 | 8 (6.6) | 0.122 |
Anti-Sp100 | 2 (1.7) | 1.000 | 2 (2.4) | 0.694 | 4 (3.3) | 1.000 |
Anti-PML | 10 (8.4) | 0.293 | 11 (12.9) | 0.311 | 15 (12.4) | 0.908 |
Anti-gp210 | 16 (13.4) | 0.540 | 9 (10.6) | 0.960 | 16 (13.2) | 0.569 |
Anti-LKM-1 | 1 (0.8) | 1.000 | 1 (1.2) | 0.496 | 0 (0.0) | 0.413 |
Anti-LC-1 | 3 (2.5) | 1.000 | 3 (3.5) | 1.000 | 4 (3.3) | 1.000 |
Anti-SLA/LP | 2 (1.7) | 0.702 | 3 (3.5) | 1.000 | 2 (1.7) | 0.688 |
Anti-Ro52 | 33 (27.7) | 0.629 | 21 (24.7) | 0.628 | 37 (30.6) | 0.356 |
P < 0.05, non-cirrhosis vs compensated cirrhosis, non-cirrhosis vs decompensated cirrhosis, and compensated vs decompensated cirrhosis, respectively. ANA: Anti-nuclear antibodies; AMA: Anti-mitochondrial antibodies; SMA: Smooth-muscle antibodies; anti-PML: Anti-promyelocytic leukemia protein; anti-LKM-1: Anti-liver kidney microsome type 1; anti-LC-1: Anti-liver cytosolic antigen type 1; anti-SLA/LP: Anti-soluble liver antigen/liver pancreas; IFA: Indirect immunofluorescence assay; LIA: Line immunoassay.