Table 3.
Characteristics of the patients according to telomerase reverse transcriptase promoter mutation status n (%)
| Variable | Overall series | TERT promoter mutated | TERT promoter non-mutated | P value |
| (n = 44) | (n = 15) | (n = 29) | ||
| Gender | ||||
| Male | 27 | 10 | 17 | 0.2059 |
| Female | 1 | 1 | 0 | |
| Age | ||||
| ≥ 60 yr | 9 | 3 (33) | 6 (67) | 0.6547 |
| < 60 yr | 19 | 8 (42) | 11 (58) | |
| Geographical origin | ||||
| African | 15 | 8 (53) | 7 (47) | 0.0528 |
| Non-African | 29 | 7 (24) | 22 (76) | |
| HBV DNA | ||||
| Positive | 23 | 6 (26) | 17 (74) | 0.2950 |
| Negative | 18 | 7 (39) | 11 (61) | |
| TP53 | ||||
| Mutated | 6 | 3 (50) | 3 (50) | 0.6315 |
| Wild-type | 38 | 11 (29) | 27 (71) | |
| MDM2 SNP 309 | ||||
| TT | 18 | 8 (44) | 10 (56) | |
| TG | 15 | 2 (13) | 13 (87) | 0.0528 (vs TT) |
| GG | 11 | 4 (36) | 7 (64) |
TERT: Telomerase reverse transcriptase; SNP: Single nucleotide polymorphism; MDM2: Murine double minute 2; HBV: Hepatitis B viral.