Table 1.
Exon | Codon | Codon change | Nucleotide change | Amino acid change |
5 | 175 | CGC→CAC | G→A | Arg→His |
7 | 245 | GGC→AGC | G→A | Gly→Ser |
7 | 245 | GGC→GAC | G→A | Gly→Asp |
7 | 248 | CGG→TGG | C→T | Arg→Trp |
7 | 248 | CGG→CAG | G→A | Arg→Gln |
8 | 273 | CGT→TGT | C→T | Arg→Cys |
8 | 273 | CGT→CAT | G→A | Arg→His |
8 | 282 | CGG→TGG | C→T | Arg→Trp |
Data selected from UMD TP53 mutation database (http://p53.fr).