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. 2014 Dec 16;10(1):54–62. doi: 10.2215/CJN.03230314

Figure 2.

Figure 2.

Macrophages are more numerous in glomeruli with FN and cellular crescents (CCs) from biopsies with pauci-immune necrotizing GN. (A) CD68+ and CD163+ macrophages are the most abundant infiltrates in glomeruli with segmental FN, exceeding polymorphonuclear neutrophils (PMNs), T cells, B cells, and natural killer cell infiltrates (data for 28 glomeruli from 14 patients; mean+SD). (B) Macrophages, PMNs, and T infiltrates are more pronounced at sites of FN and in endocapillary, extracapillary, and pericapsular sites in glomeruli with CCs. Pericapsular B cells are also more prominent in glomeruli with CCs (data for 32 glomeruli from 15 patients; mean+SD). Endo, endocapillary; Extra, extracapillary; @FN, at the site of fibrinoid necrosis; Peri, pericapsular.