Table 3.
The adjusted risks for cardiovascular morbidity or all-cause mortality according to every 1% higher relative hydration status
| Relative Hydration Status | Cardiovascular Morbidity or All-Cause Mortality | Cardiovascular Morbidity | All-Cause Mortality | |||
|---|---|---|---|---|---|---|
| Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | Hazard Ratio (95% CI) | P Value | |
| Unadjusted model | 1.09 (1.07 to 1.11) | <0.001 | 1.10 (1.07 to 1.12) | <0.001 | 1.08 (1.04 to 1.11) | <0.001 |
| Age and sex adjusted | 1.11 (1.08 to 1.13) | <0.001 | 1.11 (1.08 to 1.14) | <0.001 | 1.10 (1.05 to 1.15) | <0.001 |
| Multivariate adjusted model 1 | 1.09 (1.06 to 1.12) | <0.001 | 1.09 (1.06 to 1.12) | <0.001 | 1.09 (1.04 to 1.14) | <0.001 |
| Multivariate adjusted model 2 | 1.07 (1.03 to 1.10) | <0.001 | 1.07 (1.03 to 1.11) | 0.001 | 1.05 (0.98 to 1.11) | 0.15 |
| Multivariate adjusted model 3 | 1.08 (1.04 to 1.12) | <0.001 | 1.11 (1.06 to 1.16) | <0.001 | 1.03 (0.96 to 1.10) | 0.38 |
Multivariate model 1 is adjusted for age, sex, diabetes mellitus, cardiovascular disease, diuretics use, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers use, β-blocker, and calcium channel blocker use. Multivariate model 2 comprises model 1 as well as eGFR and log urine protein-to-creatinine ratio. Multivariate model 3 comprises model 2 as well as body mass index, serum albumin, log cholesterol, hemoglobin levels, and systolic BP.