Table 1.

Selected randomized controlled trials evaluating the effect of neostigmine in ACPO.

Author	Year	N	Agea	b	c	Conditions/patients	Dosed	Jadade	Consortf
Orlando	1994	40		16	24	Cholecystectomy: 20 Emergency surgery: 20	24 mg, nasal puff 6%	4	20
Ponec	1999	21	65.5	19	2	Recent surgery: 11 Medical condition: 10	2 mg/3–5 min	4	20
von der Spoel	2001	24	69.7			Cardiac surgery: 10 Infectious illness: 7 Cardiac illness: 4 Gastroenterological illness: 1 Gastroenterological surgery: 1 Vascular surgery 1	5 mg/50 mL NS @ 4 mL/h	4	27
Fanaei	2008	42	64	30	12	Prostatectomy: 11 patients Laparoscopic appendectomy: 10 Laparoscopic cholecystectomy: 8 Total knee replacement: 5 Hip replacement: 3 Foot amputation: 2 Lumbar laminectomy: 1 Exploratory laparotomy: 1 Open reduction/fixation of fracture: 1	2/5 mg in 500 mL NS/30 min	1	17
		127		65	38

^aReported as mean (years).

^bMale.

^cFemale.

^dDose and administration route.

^eRef. 15.

^fRef. 16.