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The architectural core of prions and amyloids. Fibers are defined both by the length of the H-bonded β-strands and β-sheet stacking, or lamination. The distance between two H-bonded peptides in a β-sheet is 4.7Å and the approximate distance between laminated β-sheets is 10Å. The amino (N) terminus is colored blue and the carboxy (C) terminus is colored red. The vertical grey arrow indicates the H-bonding direction and the typical direction of the amyloid fiber long axis.
