Fig. 1.

Overview of the SCUBA method. (Top) Structure of single-cell data. Individual cell samples are ordered by their corresponding developmental time. (Middle and Bottom) Schematic of the two main steps of SCUBA. In the bottom panel, the parameter space is divided into two regions, corresponding to one (green region and I) or two attractor states (blue region and II), respectively. The surface on top of parameter space shows the steady-state solutions corresponding to each parameter setting. Stable and unstable steady states are colored differently.