Fig. 3.

Induction of TNFSF14 by NK-cell activation receptor cross-linking. The cell surface expression of TNFSF14 and CD107 was analyzed on NK cells after coculture with P815 cells displaying antibodies against NK-cell activation receptors. P815 cells were loaded with antibodies against a single receptor or with combinations of receptors as indicated (or without antibody, labeled “Media”). K562 tumor cells were used in place of antibody-loaded P815 cells as a positive control for TNFSF14 expression and degranulation. The values indicate the percentage of cells in each quadrant. This experiment is representative of four separate experiments performed.