Fig. 3.

Characterization of trophoblast cells for the 5-HT uptake rates. Trophoblast cells were isolated and purified from normal and GDM placentas (all groups, n = 5). The [³H]-5HT uptake rates were measured in intact cells (2.3 × 10⁵ per assay) (37, 39, 45). Rate of uptake is expressed as the means and SD values of triplicate determinations from three independent samples in each group. The asterisk represents the results of a two-tailed Student t test with P < 0.001 (compared with normal trophoblast uptake rates).