Table 1.
Baseline characters of study patients and healthy subjects.
| AD Patients (n = 128) | Healthy Subjects (n = 130) | Statistical Value | p-Value | |
|---|---|---|---|---|
| Gender (male/female) | 58/70 | 60/70 | 7.3 a | 0.825 |
| Age (years) | 65.4 ± 21.0 | 65.1 ± 21.0 | 0.21 b | 0.933 |
| BMI (kg/m2) | 24.9 ± 4.8 | 25.6 ± 5.1 | 0.34 b | 0.900 |
| Diabetes/Non-diabetes | 12/116 | 12/118 | 91.9 a | 0.898 |
| High blood pressure/Normal blood pressure | 28/100 | 30/100 | 84.0 a | 0.825 |
| Coronary heart disease/Non-coronary heart disease | 26/102 | 27/103 | 89.8 a | 0.875 |
| Smoker/Non-smoker | 48/80 | 50/80 | 82.8 a | 0.923 |
| Drinker/Non-drinker | 40/88 | 43/87 | 64.9 a | 0.881 |
| Educational years | 11.6 ± 3.2 | 10.9 ± 4.1 | 1.2 b | 0.266 |
| Left-handed/Right handed | 12/116 | 14/116 | 119.0 a | 0.872 |
| During of illness (years) | 9.9 ± 6.6 | - | - | - |
| Pathological MRI (%) | 77 (60%) | - | - | - |
| Neuropsychological impairment (2 T-scores 35) (%) | 90 (70%) | - | - | - |
| MMSE scores | 19.2 ± 4.8 | 29.6 ± 2.6 | 7.71 b | 0.001 |
| CDR scale | - | - | ||
| CDR 0 | 0 | 130 | - | |
| CDR 0.5 | 60 | 0 | - | |
| CDR 1 | 38 | 0 | - | |
| CDR 2+ | 30 | 0 | - |
a χ2 test and b t-test.