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. 2014 Dec 2;15(12):22188–22202. doi: 10.3390/ijms151222188

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Main steps in the biosynthesis of terpenoids in fungi. The abbreviations used are: HMG-CoA: hydroxymethylglutaryl CoA; MVP: 5-phosphomevalonate; MVPP: 5-diphosphomevalonate; IPP: isopentenyl pyrophosphate; DMAPP: dimethylallyl pyrophosphate; FPP: farnesyl pyrophosphate. Enzymes are indicated in bold; AACT: acetoacetyl-CoA thiolase; HMGS: HMG-CoA synthase; HMGR: HMG-CoA reductase; MVK: mevalonate kinase; PMK: phosphomevalonate kinase; PMD: mevalonate 5-diphosphate decarboxylase; IDI: IPP isomerase; FPS: FPP synthase; SQS: Squalene synthase.