Fig. 2.

NK cell and ECTV-specific CTL activity. Groups of five C57BL/6, BALB/c, and A/J mice were infected with ECTV. Splenic NK cell activity (A) was measured by using ⁵¹Cr-labeled YAC-1 targets. Data shown are mean ± SEM of lysis values from five individual mice for each group at effector-to-target-cell ratio of 20:1. Anti-ECTV-specific CTL responses in the PLN (B) and spleen (C) were measured by using ⁵¹Cr release assay. Data shown are mean ± SEM of lysis values (lysis of virus-infected syngeneic targets minus lysis of uninfected targets) of pooled PLN from five mice (B) and from five individual spleens (C) at an effector-to-target-cell ratio of 20:1. The results are representative of two separate experiments.