Table 1.
Associations between clinicopathological variables and overall survival.
| Variable | Patients, n = 944 | MST (Months) | Log-Rank p | HR (95% CI) d |
|---|---|---|---|---|
| Age (years) | ||||
| ≤60 | 442 | 88 | 0.239 | 1.000 |
| >60 | 502 | 59 | 1.118 (0.927–1.349) | |
| Sex | ||||
| Male | 727 | 70 | 0.536 | 1.000 |
| Female | 217 | 63 | 1.071 (0.860–1.335) | |
| Tumor Size | ||||
| ≤5 cm | 581 | 98 | <0.001 | 1.000 |
| >5 cm | 363 | 48 | 1.422 (1.178–1.716) | |
| Location | ||||
| Non-Cardia | 626 | 78 | 0.253 | 1.000 |
| Cardia | 318 | 63 | 0.891 (0.730–1.088) | |
| Histological Types a | ||||
| Intestinal | 370 | 74 | 0.436 | 1.000 |
| Diffuse | 497 | 60 | 1.069 (0.918–1.244) | |
| Differentiation a | ||||
| Well to Moderate | 305 | 80 | 0.518 | 1.000 |
| Poorly | 493 | 59 | 1.165 (0.942–1.443) | |
| Mucinous/Signet-Ring Cell | 69 | 62 | 1.199 (0.825–1.742) | |
| Lauren a | ||||
| 1 | 399 | 76 | <0.001 | 1.000 |
| 2 | 541 | 50 | 1.467 (1.211–1.776) | |
| Depth of Invasion b | ||||
| T1 | 182 | 84 | <0.001 | 1.000 |
| T2 | 138 | 78 | 0.540 (0.408–0.714) | |
| T3 | 8 | 70 | 0.800 (0.608–1.054) | |
| T4 | 594 | 51 | 1.008 (0.416–2.442) | |
| Lymph Node Metastasis c | ||||
| N0 | 378 | 81 | <0.001 | 1.000 |
| N1/N2/N3 | 566 | 43 | 1.814 (1.480–2.222) | |
| Distant Metastasis | ||||
| M0 | 886 | 74 | 0.004 | 1.000 |
| M1 | 58 | 26 | 1.646 (1.165–2.326) | |
| TNM Stage | ||||
| I | 250 | 83 | <0.001 | 1.000 |
| II | 203 | 88 | 1.231 (0.909–1.666) | |
| III | 458 | 41 | 1.949 (1.524–2.492) | |
| IV | 25 | 44 | 2.046 (1.163–3.600) | |
| Chemotherapy | ||||
| No | 638 | 61 | 0.684 | 1.000 |
| Yes | 306 | 69 | 1.043 (0.852–1.276) |
Mean survival time was presented when the median survival time could not be measured. TNM, Tumor, Node and Metastasis; MST, median survival time; HR, hazard ratio; CI, confidence interval; AJCC, American Joint Commission on Cancer. a: Partial data were not available, and statistics were based on available data; b: Invaded depth of tumor was classified according to the criteria of AJCC 7th; c: Lymph nodes were staged according to tumor node metastasis classification of the 7th edition of AJCC in which the number of lymph nodes with a metastasis of 1–2, 3–6, and ≥7 were classified as N1, N2, and N3, respectively; d: Adjusted by age and sex.