. 2014 Dec 10;15(12):22902–22917. doi: 10.3390/ijms151222902

Table 2.

Association analyses of NR5A2 rs3790843 and rs3790844 genotypes with clinicopathological features.

Variable		rs3790843 (n = 907)			rs3790844 (n = 912)
Variable		TT	TC/CC	p	GG	GA/AA	p
Age (years)	≤60	192	237	0.610	182	249	0.380
Age (years)	>60	222	256	0.610	217	264	0.380
Sex	Male	321	375	0.601	311	391	0.539
Sex	Female	93	118	0.601	88	122	0.539
Location	Non-Cardia Cancer	279	320	0.432	264	338	0.930
Location	Cardia Cancer	135	173	0.432	135	175	0.930
Tumor Size	≤5 cm	261	302	0.581	243	324	0.486
Tumor Size	>5 cm	153	191	0.581	156	189	0.486
Lymph Node Metastasis ^a	N0	180	182	0.044	168	197	0.257
Lymph Node Metastasis ^a	N1/N2/N3	234	311	0.044	231	316	0.257
Distant Metastasis	M0	398	456	0.020	382	478	0.098
Distant Metastasis	M1	16	37	0.020	9	35	0.098
Histological Types ^b	Intestinal	168	187	0.273	156	205	0.541
Histological Types ^b	Diffuse	207	270	0.273	206	270	0.541
Differentiation ^b	Well to Moderate	137	155	0.556	127	170	0.687
	Poorly	208	267		205	270
	Mucinous/Signet-Ring Cell	30	35		30	35
Lauren ^b	1	182	199	0.253	169	218	0.450
Lauren ^b	2	229	293	0.253	227	294	0.450
Chemotherapy	No	275	333	0.721	266	348	0.709
Chemotherapy	Yes	139	160	0.721	133	165	0.709
Depth of Invasion ^c	T1	86	93	0.854	76	101	0.929
	T2	60	69		59	71
	T3	3	3		2	4
	T4	257	320		254	326
TNM Stage	I	120	118	0.369	111	128	0.533
	II	83	111		78	119
	III	198	248		198	250
	IV	10	13		9	13

HR, hazard ratio; CI, confidence interval; AJCC, American Joint Commission on Cancer; TNM, Tumor, Node and Metastasis. ^a: Lymph nodes were staged according to tumor node metastasis classification of the 7th edition of AJCC in which the number of lymph nodes with a metastasis of 1–2, 3–6, and ≥7 were classified as N1, N2, and N3, respectively; ^b: Partial data were not available, and statistics were based on available data; ^c: Invaded depth of tumor was classified according to the criteria of AJCC 7th.