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(a) The dependence of (kcat/Km)0/(kcat/Km) ratio on concentrations of BFXs (kcat/Km0 and kcat/Km denote the apparent second rate constants of NADPH oxidation in the absence and presence of BFXs as inhibitors, respectively): benzofuroxan (curve a), 5,6-methylendioxybenzofuroxan (curve b), and benzotrifuroxan (curve c); (b) The inhibition degree (ε) of NQO1 on varied concentrations of BFXs.
