Table 2.

The apparent second-order rate (k_cat/K_m) constants of reduction of BFXs and NACs by NADPH:cytochrome P-450 reductase (P-450R), pH 7.0, 25°C. All kinetic measurements were performed at fixed concentration of NADPH (150 µM).

No.	Compound	kcat/Km (M−1·s−1)
	Benzofuroxans
1.	Benzofuroxan	1.4 ± 0.2 × 103
2.	5-Methylbenzofuroxan	2.1 ± 0.1 × 103
3.	5-Dimethylbenzofuroxan	7.1 ± 0.8 × 102
4.	5-Chlorobenzofuroxan	3.2 ± 0.2 × 103
5.	5,6-Dichlorobenzofuroxan	4.3 ± 0.3 × 104
6.	5-Methoxybenzofuroxan	7.3 ± 0.3 × 102
7.	5,6-Dimethoxybenzofuroxan	5.6 ± 0.5 × 102
8.	5-Trifluorobenzofuroxan	1.1 ± 0.1 × 104
9.	5,6-Methylendioxybenzofuroxan	1.1 ± 0.1 × 103
10.	5,6-Ethylendioxybenzofuroxan	4.5 ± 0.5 × 103
11.	Benzodifuroxan	1.0 ± 0.1 × 104
12.	Benzotrifuroxan	2.9 ± 0.2 × 105
	Nitrobenzenes
13.	Nitrobenzene	2.8 ± 0.3 × 103
14.	1,2-Dinitrobenzene	2.0 ± 0.2 × 105
15.	1,3-Dinitrobenzene	4.9 ± 0.4 × 104
16.	1,4-Dinitrobenzene	2.6 ± 0.3 × 106
17.	2,4,6-Trinitrotoluene	2.3 ± 0.2 × 107