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Prevalence of typhlocolitis in telomerase deficient mice and heterozygous controls.
| Straina | Total no. | No. affected (%) | Age range (months) |
|---|---|---|---|
| TR-KO | 12 | 12 (100) | 9–13 |
| TR-heterozygous | 8 | 0 | 9–10 |
| TERT-KO | 67 | 57 (85) | 1–13 |
| 3 months or less | 11 | 3 (27) | 1–3 |
| 4 months or more | 56 | 54 (96) | 4–13 |
| TERT-heterozyous | 30 | 0 | 1.5–12 |
TERT = telomerase reverse transcriptase; mTR= murine telomerase RNA; KO=knockout; het=heterozygote
