Skip to main content
. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Ann Thorac Surg. 2014 Nov 18;99(1):270–276. doi: 10.1016/j.athoracsur.2014.08.033

Table 3. Logistic Regression for Outcome Complete Pathologic Response (Yes v. No).

pCR Univariate Logistic Regression
N N % pCR OR 95% CI p-value
Interval from end of NCRT to Surgery
Interval in weeks (continuous) 1.20 1.01-1.42 0.038
Log transformation of Interval in weeks(continuous) 6.77 1.32-34.67 0.022
By interval quartiles
≤45 Days 24 3 12.5 1.00 Ref
46-50 Days 20 4 20.0 1.75 0.34-8.95 0.50
51-63 Days 22 5 22.7 2.06 0.43-9.87 0.37
64+ Days 22 9 40.9 4.85 1.11-21.26 0.036
By 3 week intervals
3-6 weeks (26-42 days) 17 2 11.8 1.00 Ref
6.1-9 weeks (43-63 days) 49 10 20.4 1.92 0.38-9.82 0.43
9.1-12 weeks (64-84 days) 16 6 37.5 4.50 0.75-26.93 0.099
>12 weeks (85+ days) 6 3 50.0 7.50 0.85-66.12 0.070
Other Characteristics
Age (continuous) 1.04 0.99-1.09 0.16
Gender
Female 13 2 15.4 1.00 Ref
Male 75 19 25.3 1.87 0.38-9.19 0.44
T Stage
T1/T2 8 2 25.0 1.00 Ref
T3/T4 80 19 23.8 0.93 0.17-5.02 0.94
N Stage
Positive 67 16 23.9 1.00 0.99
Negative 21 5 23.8 1.00 Ref
Mstage
M0 71 19 26.8 1.00 Ref
Any M1 17 2 11.8 0.37 0.08-1.75 0.21
Histology
Adenocarcinoma 74 16 21.6 1.00 Ref
Squamous Cell Carcinoma 14 5 35.7 2.01 0.26
Type of Chemotherapy
5FU-based 71 16 22.5 1.00 Ref
Taxol-based 17 5 29.4 1.43 0.44-4.67 0.55
Type of RT
3D-CRT 72 18 25.0 1.00 Ref
IMRT 16 3 18.8 0.69 0.18-2.71 0.60

NCRT: Neoadjuvant chemoradiation

3D-CRT: 3D-conformal radiotherapy

IMRT: intensity modulated radiotherapy