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Effect of diabetes on corporal NOS activity and cGMP levels. (a) NOS activity as measured by calcium-dependent conversion of l-arginine to l-citrulline. (b) cGMP levels in control and STZ-diabetic rats corporal tissue after intracavernosal administration of vehicle, AAVCMVβgal, and AAVT19NRhoA. n, number of tissue samples; *, P < 0.05 when compared to control; **, P < 0.05 when compared to STZ-diabetic tissue treated with vehicle or AAVCMVβgal.
