Fig. 2.

Pedigrees of probands with Ank2 mutations. Females are denoted by circles, and males are denoted by squares. Hatched symbols represent humans with uncertain or unknown LQT phenotype. Open symbols represent individuals without LQT phenotype at rest. Filled symbols represent individuals diagnosed with LQT phenotype. Mutation carriers are denoted by an asterisk. Probands are marked by a star. Sudden death is denoted by SD, and death is indicated by a diagonal slash. Roman numerals indicate generations in the respective families.