Table 2.

In vitro cytotoxic activity (IC ₅₀ , μg/ml) of compounds 1a-k against breast cancer cell lines ^a

No.	Comp. Code	Cell lines
		MCF-7	MDA-MB-231	T-47D
1.	1a	57.1 ± 2.1	87.5 ± 2.5	64.3 ± 1.9
2.	1b	63.2 ± 2.6	97.3 ± 3.1	77.1 ± 2.8
3.	1c	27.1 ± 1.2	14.5 ± 2.1	76.25 ± 7.0
4.	1d	52.3 ± 2.2	43.3 ± 3.4	83.3 ± 5.2
5.	1e	78.3 ± 5.7	83.3 ± 7.2	92.3 ± 6.2
6.	1f	72.3 ± 5.5	85.3 ± 7.4	87.3 ± 7.5
7.	1 g	40.3 ± 2.8	77.4 ± 6.5	69.4 ± 5.7
8.	1 h	74.6 ± 6.5	82.3 ± 7.4	14.3 ± 1.1
9.	1i	75.3 ± 4.4	89.4 ± 6.1	79.1 ± 7.7
10.	1j	69.3 ± 5.3	45.05 ± 6.2	63.3 ± 6.6
11.	1 k	55.3 ± 5.1	19.7 ± 1.8	16.8 ± 2.1
12.	Etoposide	7.9 ± 0.5	11.1 ± 1.1	8 ± 0.8

^aThe IC₅₀ values represent an average of three independent experiments (mean ± SD).