Figure 7.
Number of autophagic and mitophagic sites (puncta) in LC3-GFP mice during sepsis. Sepsis causes a significant increase in GFP puncta per cell. Colocalization of GFP with mitochondria shows an increase in mitophagic puncta per cell in the setting of sepsis. ( * = p < 0.05 compared to LC3 puncta in WT control; # = p < 0.05 compared to colocalization in WT control)