Table 2.
Characteristics of hemodialysis patients (n = 893).
| Parameter | Type 2 DM nephropathy | Other causes of ESRD | P value |
|---|---|---|---|
| Demographic data | n = 366 | n = 527 | |
|
| |||
| Male sex, n (% of all) | 201 (54.9) | 307 (58.3) | 0.337b |
| Age at RRT beginning, years | 62.9 ± 14.1 | 57.2 ± 17.2 | <0.0001c |
| RRT duration, years | 3.29 (0.06–28.0) | 4.42 (0.12–28.2) | <0.0001c |
| Death rate, cases per 100 patient-years | 0.48 | 0.42 | |
| Death rate, cases per 100 RRT-years | 7.97 | 4.63 | |
|
| |||
| Clinical data | n = 332 | n = 527 | |
|
| |||
| Coronary artery disease, n (% of all) | 174 (52.4) | 168 (31.9) | <0.0001b |
| Myocardial infarction, n (% of all) | 98 (29.5) | 101 (19.2) | 0.009b |
| Parathyroidectomy, n (% of all) | 2 (0.60) | 21 (3.98) | 0.0009b |
| Treatment with cinacalcet hydrochloride | 24 (7.2) | 98 (18.6) | <0.0001b |
|
| |||
| Laboratory data | n = 366 | n = 527 | |
|
| |||
| Anti-HBc positive, n (% of all) | 95 (26.0) | 126 (23.9) | 0.528b |
| HBsAg positive, n (% of all anti-HBc positive) | 7 (7.4) | 11 (8.7) | 0.807b |
| Anti-HCV positive, n (% of all) | 26 (7.1) | 57 (10.8) | 0.062b |
| HCV RNA positive, n (% of all anti-HCV positive) | 14 (53.8) | 39 (68.4) | 0.225b |
| Responders to hepatitis B vaccine, n (% of all) | 202 (55.2) | 315 (59.8) | 0.191b |
| 25(OH)D (ng/mL)a | 13.3 ± 3.9 | 14.5 ± 5.6 | 0.182a,d |
| Total calcium (mg/dL) | 8.83 ± 0.67 | 8.91 ± 0.82 | 0.264d |
| Phosphates (mg/dL) | 5.03 ± 1.44 | 5.25 ± 1.49 | 0.054d |
| PTH (pg/mL) | 296 (12.9–3,757) | 463 (12.7–3,741) | <0.0001c |
| Total alkaline phosphatase (U/L) | 98.2 (25.8–1,353) | 97.1 (40.5–1,684) | 0.528c |
25(OH)D: 25-hydroxycholecalciferol, anti-HBc: antibodies to core antigen of hepatitis B virus, anti-HCV: antibodies to hepatitis C virus, HBsAg: surface antigen of hepatitis B virus, DM: diabetes mellitus, ESRD: end-stage renal disease, HCV RNA: ribonucleic acid of hepatitis C virus, PTH: parathyroid hormone, and RRT: renal replacement therapy.
A significant difference is indicated using bold font.
a n = 66 for type 2 DM nephropathy; n = 96 for other renal diseases.
bFisher's exact test.
cMann-Whitney test.
dUnpaired t-test, Welch corrected.