Table 1.

Physical and chemical properties of the antibiotics investigated

^aSciFinder Scholar database (American Chemical Society 2007).

^bConstant K = 0.96 + 0.091 · ln (partition coefficient / molecular weight^1/2).

^cCSF(cerebrospinal fluid)/free plasma area under the curve ratio adopted from a study evaluating CSF penetration of teicoplanin. 90% of protein binding was considered also (Reference 8).