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. 2015 Jan 6;8:423. doi: 10.3389/fnins.2014.00423

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Copyright © 2015 Obien, Deligkaris, Bullmann, Bakkum and Frey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Array architectures. This table summarizes and classifies the different architectures that are typically used for MEAs. Advantages, disadvantages are stated and representative selected references given. (A,B) Fixed wiring. (A) Electrodes are directly connected to signal pads with no active circuitry. (B) Electrodes are directly connected to on-chip active circuitry for signal conditioning. (C–E) Multiplexed arrays. (C) Signals are multiplexed to the signal pads via column, row addressing in static mode. (D) More flexible addressing is achieved by adding more routing resources within the array in the switch-matrix mode. (E) All electrodes can be sampled at fast speeds in full-frame readout implemented in active pixel sensor (APS) MEAs.