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. 2013 Dec 30;66(1):24–30. doi: 10.1002/art.38196

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© 2014 The Authors. Arthritis & Rheumatology is published by Wiley Periodicals, Inc. on behalf of the American College of Rheumatology

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Manhattan plots showing P values for genetic association with rheumatoid arthritis (RA) in the original Wellcome Trust Case Control Consortium genome-wide association study (GWAS) (a) and the expanded UK GWAS (b). Panels are truncated at a −log₁₀P value of 35. Single-nucleotide polymorphisms having an association with RA at genome-wide levels of significance are shown above the horizontal red line.