Table 3. Results of regression analysis for variables predicting treatment outcomes for 100 children with tularemia, Ankara, Turkey, September 2009–November 2012*.
| Variable |
Treatment failure |
|
Spontaneous suppuration |
|
Relapse |
|
Requirement for surgical procedures |
| OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Female sex | 3.449 (1.250–9.514) | 0.017 | 1.348 (0.313–5.804) | 0.689 | 2.314 (0.850–6.300) | 0.101 | 1.842 (0.716–4.742) | 0.205 | |||
| Treatment delay >16 d |
3.277
(1.220–8.799) |
0.019 |
|
6.074
(1.185–31.131) |
0.030 |
|
1.295
(0.477–3.517) |
0.612 |
|
1.876
(0.741–4.751) |
0.184 |
| Antimicrobial drug | |||||||||||
| GEN† | 0.067 | ND | ND | 0.643 | 0.140 | ||||||
| DOX | 4.965 (1.280–19.264) | 0.021 | ND | ND | 1.295 (0.355–4.733) | 0.695 | 3.308 (0.957–11.428) | 0.059 | |||
| CIP | 2.637 (0.733–9.483) | 0.138 | ND | ND | 0.542 (0.124–2.371) | 0.416 | 2.689 (0.808–8.950) | 0.107 | |||
| GEN + DOX |
0.458
(0.060–3.473) |
0.450 |
|
ND |
ND |
|
0.376
(0.035–4.033) |
0.419 |
|
0.636
(0.094–4.317) |
0.643 |
| Age at diagnosis | 0.926 (0.832–1.031) | 0.162 | 0.941 (0.755–1.173) | 0.589 | 0.925 (0.801–1.067) | 0.283 | 0.935 (0.841–1.041) | 0.219 | |||
| Age at study inclusion | 2.611 (0.739–9.222) | 0.136 | 2.096 (0.151–29.018) | 0.581 | 2.588 (0.476–14.086) | 0.271 | 2.321 (0.658–8.183) | 0.190 |
*Because the number of patients was limited, antimicrobial drugs were not included in the regression analysis for spontaneous suppuration. CIP, ciprofloxacin; DOX, doxycycline; GEN, gentamicin; ND, not done. †Reference variable.