Table 6.
Content of the marker compounds in single herbs and the combinational herbs of JGT (μg/mL)
| Compound | PL single (2 g) | PL (2 g) + GU | PL single (2 g) | PL (2 g) + GU-SB | ||||
|---|---|---|---|---|---|---|---|---|
| GU (2 g) | GU (4 g) | GU (8 g) | GU-SB (2 g) | GU-SB (4 g) | GU-SB (8 g) | |||
| Gallic acid | 59.55 ± 0.95 | 50.17 ± 0.46b) (84.25%) | 40.34 ± 0.27b) (67.74%) | 33.09 ± 0.11b) (55.56%) | 59.55 ± 0.95 | 48.00 ± 0.11b),d)) (80.61%) | 36.45 ± 0.14b),f) (61.21%) | 29.92 ± 0.21b),f) (50.24%) |
| Oxypaeoniflorin | 21.70 ± 0.29 | 20.04 ± 0.07b) (92.35%) | 18.60 ± 0.16b) (85.68%) | 14.71 ± 0.19b) (67.78%) | 21.70 ± 0.29 | 19.92 ± 0.08b) (91.78%) | 18.00 ± 0.33b) (82.92%) | 14.94 ± 0.27b) (68.83%) |
| (+)-Catechin | 7.72 ± 0.59 | 6.27 ± 0.12b) (81.21%) | 4.41 ± 0.07b) (57.12%) | 1.78 ± 0.05b) (23.00%) | 7.72 ± 0.59 | 7.07 ± 0.24e) (91.62%) | 6.61 ± 0.43b),e) (85.59%) | 5.35 ± 0.26b),f) (69.32%) |
| Albiflorin | 28.90 ± 0.30 | 30.80 ± 0.65b) (106.60%) | 29.98 ± 0.68 (103.73%) | 28.53 ± 0.52 (98.73%) | 28.90 ± 0.30 | 29.46 ± 0.67 (101.95%) | 31.13 ± 0.43b) (107.74%) | 31.82 ± 0.50b),e) (110.11%) |
| Paeoniflorin | 494.34 ± 2.12 | 441.51 ± 2.00b) (89.31%) | 406.10 ± 3.45b) (82.15%) | 301.12 ± 0.35b) (60.91%) | 494.34 ± 2.12 | 468.46 ± 3.87b),e) (94.77%) | 411.86 ± 3.47b) (83.31%) | 348.46 ± 4.05b),e) (70.49%) |
| Benzoic acid | 24.94 ± 0.17 | 27.05 ± 0.71 (108.44%) | 27.16 ± 0.80 (108.87%) | 28.71 ± 0.88b) (115.09%) | 24.94 ± 0.17 | 26.91 ± 0.67 (107.87%) | 26.42 ± 1.23 (105.91%) | 27.69 ± 2.35 (111.02%) |
| Benzoylpaeoniflorin | 13.16 ± 0.07 | 11.46 ± 0.59 (87.12%) | 10.60 ± 2.39 (80.57%) | 8.38 ± 2.82b) (63.67%) | 13.16 ± 0.07 | 11.59 ± 0.56 (88.08%) | 9.65 ± 0.46a) (73.37%) | 8.36 ± 0.33b) (63.54%) |
| Compound | GU single (2 g) | PL + GU (2 g) | GU-SB single (2 g) | PL + GU-SB (2 g) | ||||
|---|---|---|---|---|---|---|---|---|
| PL (2 g) | PL (4 g) | PL (8 g) | PL (2 g) | PL (4 g) | PL (8 g) | |||
| Liquiritin | 282.18 ± 0.72 | 236.07 ± 0.74b) (83.66%) | 188.03 ± 1.16b) (66.64%) | 143.27 ± 0.58b) (50.77%) | 153.39 ± 0.42f) | 132.69 ± 0.47b),f) (86.51%) | 129.07 ± 0.58b),f) (84.14%) | 86.07 ± 0.73b),f) (56.11%) |
| Isoliquiritin | 16.04 ± 0.09 | 12.71 ± 0.07b) (79.19%) | 4.68 ± 0.01b) (29.18%) | 2.71 ± 0.01b) (16.91%) | 10.06 ± 0.06f) | 6.93 ± 0.04b),f) (68.85%) | 5.29 ± 0.02b),f) (52.61%) | 0.73 ± 0.01b),f) (7.22%) |
| Ononin | 17.33 ± 0.24 | 13.05 ± 0.13b) (75.30%) | 8.05 ± 0.07b) (46.43%) | 5.69 ± ± 0.05b) (32.83%) | 16.50 ± 0.10d) | 11.85 ± 0.04b),e) (71.80%) | 10.12 ± 0.02b),f) (61.31%) | 6.16 ± 0.01b),e) (37.33%) |
| Glycyrrhizin | 488.99 ± 1.33 | 379.76 ± 0.93b) (77.66%) | 303.80 ± 1.23b) (62.13%) | 223.04 ±0.65b) (45.61%) | 569.02 ± 0.64f) | 438.93 ± 0.69b),f) (77.14%) | 375.43 ± 0.39b),f) (65.98%) | 273.50 ± 0.14b),f) (48.07%) |
a)
p < 0.05.
b)
p < 0.01.
c)
p < 0.001 versus single herb group.
d)
p < 0.05.
e)
p < 0.01.
f)
p < 0.001 between GU and GU-SB groups.